Centre for metabolomics research

Roy Goodacre and colleagues in the Centre for Metabolomics Research are based in Liverpool University in the Department of Biochemistry within the Institute of Integrative Biology.  In the CMR we develop and apply robust and reproducible metabolomics platforms that can be used in human, plant and microbial studies and have generated metabolomics standards and procedures (SOPs) that have been very well received by the metabolomics community.  We apply metabolomics to all areas of biology with an aim to understand systems at the cellular, tissue and whole organism level.

 We have strong interdisciplinary skills that are complementary in nature as metabolomics is a multidisciplinary science that spans different areas of biology, analytical chemistry and computer sciences. We have focus on GC-MS for analysis of polar, non-volatile analytes and combine this with several LC-MS platforms with ion mobility, triple quad separation for quantification, and the latest Orbitrap Tribrid-XL technologies.

 As well as working in mass spectrometry-based metabolomics we also work in NMR spectroscopy (600 MHz and 700 MHz spectrometers fitted with Samplejet autosamplers) and are unique in that in parallel we are developing complementary chemical imaging methods based on high spatial resolution Raman, stimulated Raman and photothermal infrared spectroscopies.

Follow the Centre for Metabolomics Research on Twitter: @LivUniCMR